Hello Sukumar, Hello! Thank you for your question. Our Plix Apple Cider Vinegar products are generally considered safe and effective for most people when taken as directed. However, if you have a thyroid condition and are taking medication for it, we recommend consulting with your doctor before taking any new supplements, including our Plix products.Some studies have suggested that apple cider vinegar may interact with certain medications, including thyroid medication, so it's important to check with your doctor first to ensure that our product is safe for you to use.That being said, we have many customers who have reported positive results with our ACV products, including improved digestion, reduced bloating, and even weight loss. Our products are made with natural, high-quality ingredients and do not contain any harmful or synthetic ingredients.Thank you for considering Plix, and we wish you all the best on your health journey. Take Care, Have Fun!